Gabrielle A. Stryker, Assistant Professor Science Building, Room 236C 400 E. University Way Ellensburg, WA 98926-7537 (509) 963-2721 email: strykerg@cwu.edu

Education

Teaching

General Biology, Microbiology, Immunology, Parasitology

Research

My primary research involves investigations into the vaccine potential of the paraflagellar rod proteins of Trypanosoma cruzi, the agent of Chagas' disease. A second line of research currently ongoing is a collaborative mathematical modelling project with Dr Anna Spagnuolo, studying the dynamics of Chagas' disease with insecticide spraying of endemic villages.

Peer-reviewed Publications:

• Clark, AK., Kovtunovych, G., Kandlikar, SS., Lal, SK. and Stryker, GA. 2005 Cloning and expression analysis of two novel paraflagellar rod domain genes found in Trypanosoma cruzi. Parasitology Research 96(5):312-320.
• Shen, Z., Stryker, GA., Mernaugh, R, Yu, L., Yan, H, Zeng, X. 2005. Single-chain Fragment Variable (scFv) Antibody Piezoimmunosensors. Analytical Chemistry 77(3):797-805.
• Gupta, S., Wang, B., Stryker, GA., Zanetti, ME. and Lal, SK. 2004 Two Novel Arginine/Serine (SR) Proteins in Maize are differentially Spliced and Utilize Non-Canonical Splice Sites. Biochimica et Biophysica Acta - Gene Structure and Expression 1728(3):105-114.
• Gupta, S., Gallavotti, A., Stryker, GA., Schmidt, RJ., and Lal, SK. 2004 A novel class of Helitron- related transposable elements in maize contain portions of multiple pseudogenes. Plant Molecular Biology 57(1):115-127.
• Hanna, DM., Oakley, BA., and Stryker GA. 2003. Using a System-on-a-Chip Implantable Device to Filter Circulating Infected Cells in Blood or Lymph. IEEE Transactions on Nanobioscience 2(1): 6 -13.
• Fouts, DL., Stryker, GA., Gorski, K., Miller, MJ., Nguyen, TV., Wrightsman, RA., and Manning, JE. 1998. Evidence for four distinct major protein components in the paraflagellar rod of Trypanosoma cruzi. Journal of Biological Chemistry 273(34):21846-21855.
• Miller, MJ., Wrightsman, RA., Stryker, GA., and Manning, JE. 1997. Protection of mice against Trypanosoma cruzi by immunization with paraflagellar rod proteins requires T cell but not B cell function. Journal of Immunology 158(11):5330-5337.

Peer-reviewed Conference papers:

• Oakley, BA., Gross, BA., Martens, SG., Hanna, DM., and Stryker, GA. 2006. "Electroporation-Induced Cell Lysis in SWLA-2 Hybridomas" Engineering in Medicine and Biology Society. Proceedings of the 28th Annual International Conference of the IEEE, Accepted
• Hanna, DM., Gross, BA., Kandlikar, SS., Lempicki, E., Oakley, BA., Stryker, GA. 2005. Detection of Vesicular Stomatitis Virus using a Capacitive Immunosensor. Engineering in Medicine and Biology Society. Proceedings of the 27th Annual International Conference of the IEEE 27:534-537.
• Oakley, BA., Hanna, DM., Kandlikar, SS., Gross, BA., Stryker, GA. 2005. Cell Lysis in SWLA-2 Hybridomas due to 1 kHz AC Electric Fields. Engineering in Medicine and Biology Society. Proceedings of the 27th Annual International Conference of the IEEE 27:1268-1289.
• Kandlikar, SS., Oakley, BA., Hanna, DM., Stryker, GA. 2004. "An Examination of the Effect of Decaying Exponential Pulse Electric Fields on Cell Mortality in Murine Spleenocytes, Hybridomas, and Human Natural Killer Cells," Engineering in Medicine and Biology Society. Proceedings of the 26th Annual International Conference of the IEEE 26:2643-2646.
• Gross, BA., Kandlikar, SS., Oakley, BA., Hanna, DM., Rusek, A., Stryker, GA. 2004. "An Examination of the Effect of an AC Pulsed Electric Field on Cell Mortality in SWLA-2 Hybridomas," Engineering in Medicine and Biology Society. Proceedings of the 26th Annual International Conference of the IEEE 26:2635-2638.
• Spagnuolo, AM., Hanna, DM., Lindsey, W., and Stryker, GA. 2004. "Modeling HIV-1 Dynamics and the Effects of Decreasing Activated Infected T-cell Count by Filtration," Engineering in Medicine and Biology Society. Proceedings of the 26th Annual International Conference of the IEEE 26:722-725.