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IACUC

General Internet Resources

Staying Connected: Internet Resources for the Institutional Animal Care & Use Committee

Based on a document originally prepared by: Julie Watson, Consulting Veterinarian & Coral Wigglesworth, Senior Policy Analyst, OLAW

Search Strategies

There are a wide variety of search engines available for tracking down information on the world wide web (e.g. www. yahoo.com or www. altavista.com or www. infoseek.com). Remember, though, that no search engine covers more than a third of the estimated total indexed pages, and the drawback to using search engines is that it takes technique and time to get relevant results.

Where to Begin

The fastest method when you're looking far information and don't have a good address is often to start from a focused database such as NetVet, or from another highly relevant site. This also has the advantage of letting the site maintain the various critical links, so you don't have to do it!

IACUC.ORG is an information resource for IACUC members and staff, developed with funding from AALAS. It was developed as on organizing tool to quickly point to a topic of interest, helping IACUC members manage the overwhelming amount of information available on the web.

www.iacuc.org

The Animal Welfare Information Center is another great starting point, linking you to everything an IACUC member could ever need or want.

www.nal.usda.gov/awic

NetVet covers a huge array of topics and hot links and can get you to almost anything that is animal-related, However, the down side is that because there is so much information, it can still take a little while to track things down.

http://netvet.wustl.edu/vet.htm

The Canadian Council on Animal Care site contains a wealth of information on animal care and use. They have policies and guidelines on every aspect of animal welfare and much of this information is applicable in the US as well.

www.ccac.ca

Essential Online References

This link from the AWIC site gives you full text versions of the complete Animal Welfare Act and Regulations.

www.nal.usda.gov/awic/legislat/usdaleg1.htm

Online APHIS Animal Care Policy Manual includes the 29 (and counting...) official policy documents that clarify the intent of the Animal Welfare Act.

http://www.aphis.usda.gov/ac/polmanpdf.html

The Health Research Extension Act of 1985 , 'Animals in Research'.

http://grants.nih.gov/grants/olaw/references/hrea1985.htm

The PHS Policy on Humane Care and Use of Laboratory Animals applies to all facilities that receive NIH grant support.

http://grants.nih.gov/grants/olaw/references/phspol.htm

The Guide for the Care and Use of Laboratory Animals is an IACUC must read! PHS Policy incorporates these guidelines by reference.

www.nap.edu/readingroom/books/labrats/

The 2007 version of the AVMA Guidelines on Euthanasia sets the standards for euthanasia practices. PHS Policy incorporates these guidelines by reference.

http://www.aphis.usda.gov/animal_welfare/downloads/reports_out/euthanasia.pdf

This 1996 ACLAM Report on Adequate Veterinary Care clarifies the expectations and requirements for an institution's veterinary care program.

http://www.aclam.org/Content/files/files/Public/Active/position_adeqvetcare.pdf

A listing of all of ILAR publications can be found at:

http://dels.nas.edu/ilar/pubs

A quick guide to the ever-useful AWIC Bibliographies .

http://awic.nal.usda.gov/publications/bibliographies-and-resource-guides

USDA/APHIS Animal Care

http://www.aphis.usda.gov/ac/

Public Health Service: Office of Laboratory Animal Welfare (OLAW)

http://grants.nih.gov/grants/olaw/

Note particularly the useful sample documents & forms located at...

http://grants.nih.gov/grants/olaw/sampledoc/index.htm

Laws. Regulations and Government Resources

NetVet Law and Government Resources is a very extensive list of hotlinks organized alphabetically according to which branch of the government you are dealing with. In fact, it is so extensive that it is almost 'too much of a good thing.'

http://netvet.wustl.edu/law.htm

The " Thomas " site has everything you ever wanted to know about the legislative process and more.

http://thomas.loc.gov/

The National Archives and Records Administration - Government Printing Office ( GPO access ) site allows you quick access to the Federal Register.

http://www.gpoaccess.gov/fr/index.html

Food and Drug Administration site, with links to all Centers.

www.fda.gov

Species-Specific Resources

The Whole Mouse Catalog is geared to researchers, but could be useful resource for IACUC members, for example for localizing a hybridoma bank as an alternative to ascites production, description and sources of inbred strains, background information on transgenes and transgenic research.

www.rodentia.com/wmc/

The University of Michigan 's Transgenic Animal Model Core web site is a very valuable resource on all aspects of transgenic animal care and oversight.

www.med.umich.edu/tamc

A branch of the virtual library , this is a comprehensive list of animal-related organizations (over 6000) and sites (over 1000) plus listings for endangered species and animal sites (in general for the non-professional) categorized by species.

http://www.a25.com/

Model Organisms for Biomedical Research is a site sponsored by NIH, providing information on the use of rats, mice and non-mammalian species in research.

www.nih.gov/science/models/

This link will connect you with the Laboratory Primate Newsletter , which serves as a central source of practical information about establishing and running a facility with caged nonhuman primates. The site contains lots of links to information on primate enrichment.

www.brown.edu/Research/Primate/

Primate fact sheets from the Primate Info Net at Wisconsin Regional Primate Research Center .

http://pin.primate.wisc.edu/aboutp/factsheets/

Training

This IACUC tutorial is not flashy, but it is a good orientation to the Animal Welfare Regulations and PHS policy for new IACUC members.

http://grants.nih.gov/grants/olaw/tutorial/index.htm

This 2002 version of the ARENA/OLAW IACUC Guidebook is an excellent resource for training or reference.

http://grants.nih.gov/grants/olaw/guidebook.pdf

The Laboratory Animal Welfare Training Exchange (LAWTE) aims to promote an information exchange among laboratory animal welfare trainers on training programs, systems, materials and services for the purpose of promoting the highest standards of laboratory animal care and use.

www.lawte.org

ILAR Principles for the Use of Animals in Precollege Education (1989). This three page document describes the 10 basic principles and can be found as link on the ILAR site.

http://dels.nas.edu/ilar/prin_guide.asp

The Laboratory Animal Training Association site provides a guide to training resources, as well as online training, which is available for a fee.

www.latanet.com/

Occupational Health and Safety

This 1997 ILAR publication, Occupational Health and Safety in the Care and Use of Research Animals , is posted in graphic format.

www.nap.edu/catalog/4988.html

Many of the listed sites on OSHWEB appear to be geared to the occupational health and safety professional rather than the IACUC member. However, this is a very comprehensive listing, including information on radiation safety, chemical safety, and occupational health.

http://www.oshweb.com/

This OSHA site includes a fairly useful listing of occupational health and safety organizations , and a few institutional departments.

Ethical Use of Animals in Research

On being a scientist -- responsible conduct of research . National Academy of Sciences 1985.

www.nap.edu/readingroom/books/obas

Guidelines for Ethical Conduct in the Care and Use of Animals from the American Psychological Association . An extensive and fairly practical series of guidelines for humane use of animals in research, especially useful for giving IACUCs guidance on the acceptability of various commonly-used procedures in psychology experiments.

www.apa.org/science/anguide.html

NASA Principles for the Ethical Care and Use of Animals.

http://grants.nih.gov/grants/olaw/references/dc97-2.htm

Comprehensive Institutional Sites

Pennsylvania State University has a nicely organized site that is easy to navigate. All of their forms and policies are available in either html or pdf formats.

http://www.research.psu.edu/arp/

Rutgers Laboratory Animal Services 'homecage' links you to a variety of resources, including their Animal Care Manual and a semiannual program review checklist developed by Dr. Stephen Curtis.

http://las.rutgers.edu/

University of Arizona 's University Animal Care page has links to their IACUC Handbook and to training modules.

www.ahsc.arizona.edu/uac/

University of California, Davis ' site includes policy statements, protocol templates, policy and procedure manual excerpts, page of reference documents with links, and 11 autotutorials.

http://ehs.ucdavis.edu/animal/index.cfm

University of California, Santa Barbara 's Animal Care Committee page includes tips on searching for alternatives, information on zoonotic diseases, and training information on individual species.

http://research.ucsb.edu/iacuc/iacuc.shtml

University of Florida 's IACUC page includes IACUC guidelines, IACUC review process, animal use approval forms, graphs of USDA trends of animal use for last 3 and last 20 years, species-specific information, and guidance on assigning pain categories.

http://iacuc.ufl.edu/

University of Iowa 's site has information on alternatives searching, as well as guidelines on monoclonal antibody production and the ascites model.

http://research.uiowa.edu/animal/

The University of Michigan 's Committee on the Use & Care of Animals site has a link to a wide array of forms and documents relevant to IACUC function.

http://www.ulam.umich.edu/

University of Missouri 's Animal Care and Use Committee site is visually appealing and includes their forms, policies, tips on how to conduct a facility inspection, and a great Q&A on personnel qualifications for working with animals.

http://oar.missouri.edu/OAR/insideoar/links.htm

Wayne State University 's site information was provided after the MISMR meeting by Dr. Merlyn Ekstrom. Check it out.., a very useful site! Includes a very comprehensive online resource manual.

http://dlar.wayne.edu/

North Dakota State U IACUC Newsletter table of contents. Various issues provide succinct overviews on such topics as: USDA policy on painful procedures; consideration of alternatives: documentation; IACUC review of field studies.

http://www.ndsu.edu/pubweb/~gerst/

Animal Welfare Organizations

These organizations can be of great assistance to you in staying current on animal welfare-related issues, regulations, accreditation standards, and current practices.

American Association for Laboratory Animal Science - now includes a wonderful site for kids!

www.aalas.org

www.kids4research.org/

American College of Laboratory Animal Medicine (ACLAM)

www.aclam.org

American Committee on Laboratory Animal Diseases (ACLAD)

http://www.aclad.org/

Americans for Medical Progress (AMP)

www.ampef.org

Applied Research Ethics National Association (ARENA)

http://www.primr.org

Association for the Assessment & Accreditation of Laboratory Animal Care (AAALAC)

International

www.aaalac.org

Institute of Laboratory Animal Research (ILAR)

http://dels.nas.edu/ilar/

Michigan Society for Medical Research (MISMR)

www.mismr.org

National Association for Biomedical Research (NABR)

www.nabr.org

Public Responsibility in Medicine & Research ( PRIM&R)

http://www.primr.org

Scientists Center for Animal Welfare (SCA W), including IACUC TALK forum.

www.scaw.com

http://www.scaw.com/iacuctalk.html

 Animal Welfare, Rights, Humane, and Rescue Organizations-

The following list maintained by NETVET is a comprehensive compilation of the full range of animal welfare, rights, humane, and rescue organizations.

http://netvet.wustl.edu/welfare.htm