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Chemistry

P. Whitney Swain III

Lecturer, Biochemistry

Phone:  (509) 963-2815
Fax:  (509) 963-1050
Email:  swainp@cwu.edu

CWU Coursework

  • Chemistry 111
  • Biochemistry 113, 431, 432

Education

  • Ph D., 2010, Chemistry, The University of Montana, Missoula.  “Synthesis and Structure Activity Relationship Studies of Natural Product-Derived Compound Libraries”  Advisor: Dr. Nigel D. Priestley
  • B.S., 2004, Biochemistry (ACS), Indiana University.

Professional Experience:

  •   2010-2013:  Promiliad Biopharma, Inc.                                     
  • Minimum inhibitory concentration determination/bioassays against BSL-1 and BSL-2 organisms
  • Animal studies with CD-1 outbred mice: biological burden assays, pharmacokinetics, maximum tolerated dosage, tissue collection, surgical procedures
  • Genomic sequencing studies and analyses
  • Protein expression, purification and development of in vitro enzymatic assays
     
  • 2010-2012: Guest Lecturer, University of Montana; Organic Chemistry 221-222
  • Teaching Assistantships:

Quantitative Analysis and Instrumental Methods 
Biochemistry Research Lab
Fundamentals of Biochemistry
Organic Chemistry Lecture and  Lab

Publications:

1)   Viswanathan, Kishore; Frey, Kathleen M.; Scocchera, Eric W.; Martin, Brooke D.; Swain III, P. Whitney; Alverson, Jeremy B.; Priestley, Nigel D.; Anderson, Amy C.; Wright, Dennis L.  Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes. PLoSOne (2012) vol. 7(2).

2) Sumskaya, Yuliya G.; Swain III, P. Whitney; Bergmeier, Stephen C.; McMills, Mark C.; Priestley, Nigel D.; Wright, Dennis L. Natural Feedstocks for Diversity-Oriented Synthesis: Macrolide-Like Scaffolds From Nonactate. Arkivoc (2011) Part v. 144-166.

3)   Phillips, Joshua B.; Smith, Adrienne E.; Kusche, Brian R.; Bessette Jr., Bradley A.; Swain III, P. Whitney; Bergmeier, Stephen C.; McMills, Mark C.; Wright, Dennis L. and Priestley, Nigel D.  Natural Product Derivatives with Bactericidal Activity Against Gram-positive Pathogens Including Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus faecalis.  Bioorganic & Medicinal Chemistry Letters (2010) 20, 5936-5938.